London, United Kingdom
+44 20 3893 3227

Decoding Ovary Pain: A Comprehensive Guide to Understanding and Managing Potential Causes

7 Potential Causes of Ovary Pain: How They’re Diagnosed and Treated

Introduction: Ovary pain can occur due to various conditions and can affect one or both sides of the pelvis, as well as the back or thighs. It may be accompanied by pain during sex, urination, or excessive cramping during periods. The ovaries play a vital role in reproduction, producing eggs and hormones such as estrogen and progesterone. While ovary pain is often related to the menstrual cycle, it can also indicate an underlying health issue. In this article, we will explore seven potential causes of ovary pain, including their symptoms, diagnosis, and treatment options.

1. Mittelschmerz: Mittelschmerz refers to the ovary pain experienced by some individuals during regular ovulation each month. This pain occurs around day 14 of the menstrual cycle when the egg is released from the ovary into the fallopian tube. The exact cause of ovulation pain is not fully understood, but theories suggest that the rupture of the ovarian wall or the enlargement of the egg before ovulation may contribute to the discomfort.

  • Symptoms:

    • Discomfort in the pelvis on one side, corresponding to the ovary releasing the egg.
    • Mild to sharp and sudden pain lasting from a few minutes to several hours.
    • Possible bleeding or discharge during ovulation.
    • Nausea in some cases.
  • Diagnosis:

    • Timing of pain and pelvic examination.
    • Keeping a pain diary to track symptoms.
  • Treatment:

    • Over-the-counter pain medication (e.g., acetaminophen or ibuprofen) for pain relief.
    • Birth control pills to suppress ovulation if pregnancy is not desired.

2. Ovarian Cysts: Ovarian cysts are fluid-filled sacs or pockets that can develop on the surface of an ovary. Functional cysts, which form during the menstrual cycle, are the most common type and often resolve on their own. Other types, such as endometriomas, dermoid cysts, and cystadenomas, can also occur. While most ovarian cysts are benign, postmenopausal individuals have a higher risk of developing malignant cysts.

  • Symptoms:

    • Pelvic pain, lower back and thigh pain, pain during periods and sex.
    • Abdominal fullness, unusual vaginal bleeding, breast tenderness.
    • Pressure on the bladder, frequent urination, difficulty emptying the bladder or bowel.
  • Diagnosis:

    • Pelvic exam to detect the presence of a cyst.
    • Additional tests like pregnancy test, transvaginal ultrasound, and CA125 blood test.
  • Treatment:

    • “Wait and see” approach for cysts likely to resolve on their own.
    • Pain medications for symptom relief.
    • Hormonal birth control to prevent ovulation and reduce cyst formation.
    • Surgical removal for cysts that persist, cause significant pain, or appear atypical.

3. Endometriosis: Endometriosis occurs when tissue similar to the endometrium grows outside the uterus, leading to pain and other symptoms. The ovaries are commonly affected by this misplaced tissue, causing pelvic pain, dysmenorrhea, and discomfort during sexual intercourse or urination.

  • Symptoms:

    • Severe menstrual cramps, chronic pelvic or lower back pain.
    • Pain during or after sex, painful urination or bowel movements.
    • Digestive discomfort, fatigue, infertility.
  • Diagnosis:

    • Thorough history and pelvic exam.
    • Imaging techniques like ultrasound and MRI.
    • Laparoscopy for definitive diagnosis and visualization of endometriosis lesions.
  • Treatment: -Medications to alleviate symptoms:

    • Hormonal birth control to regulate menstrual cycles and reduce pain.
    • Gonadotropin-releasing hormone agonists to induce temporary menopause.
    • Over-the-counter pain medications for mild pain relief.
  • Surgical options:

    • Laparoscopic surgery to remove endometriosis lesions and scar tissue.
    • Biopsy of tissue samples for further examination.

Conclusion: Ovary pain can stem from various causes, including mittelschmerz, ovarian cysts, and endometriosis. Recognizing the symptoms and seeking medical evaluation is important for accurate diagnosis and appropriate treatment. While some conditions can be managed with pain medications and hormonal therapies, others may require surgical intervention. In the next sections of this article, we will explore additional potential causes of ovary pain and their respective diagnosis and treatment options.

4. Pelvic Inflammatory Disease (PID)

Pelvic inflammatory disease (PID) is an infection that affects the reproductive organs in individuals with ovaries. It primarily involves the cervix, uterus, fallopian tubes, and ovaries. While PID can be sexually transmitted, it can also occur due to other types of infections. It is most commonly observed in women of reproductive age.

  • Causes:

    • Various bacteria can cause PID, with gonorrhea and chlamydia being responsible for approximately one-third of reported cases.
  • Symptoms:

    • Pelvic or abdominal pain and tenderness.
    • Burning sensation during urination.
    • Frequent urination.
    • Irregular bleeding.
    • Changes in vaginal discharge.
    • Pain during sex.
    • Fever with or without chills.
  • Diagnosis:

    • Pelvic exam to assess inflammation and tenderness.
    • Culturing of vaginal or cervical samples to identify the infection.
    • STI tests for gonorrhea and chlamydia.
    • Blood and urine tests to detect signs of inflammation and rule out other conditions.
    • Additional procedures like pelvic ultrasound, endometrial biopsy, or laparoscopy may be used to confirm the diagnosis and evaluate organ damage.
  • Treatment:

    • Antibiotics to clear the infection. Completing the full course of antibiotics is essential.
    • Treatment for sexual partners to prevent reinfection.
    • Surgery may be required in rare cases where an abscess has formed or ruptured.

5. Ovarian Torsion

Ovarian torsion refers to the twisting of an ovary around its supporting ligaments within the pelvic area. This rotation can disrupt the blood supply to the ovary, leading to tissue damage.

  • Causes:

    • Commonly occurs due to the presence of a mass on the ovary, such as an ovarian cyst, polycystic ovarian syndrome (PCOS), or a tumor.
    • Pregnancy and fertility treatments can increase the risk of ovarian torsion.
  • Symptoms:

    • Sudden and severe pelvic pain radiating to the abdomen, back, or flank.
    • Nausea and vomiting.
    • Symptoms may be intermittent if the ovary twists and untwists.
  • Diagnosis:

    • Laboratory tests to rule out other conditions.
    • Transvaginal or pelvic ultrasound to visualize the affected ovary and assess blood flow.
    • Definitive diagnosis during corrective surgery.
  • Treatment:

    • Surgery to untwist the ovary and, if necessary, remove any cysts present.
    • Laparoscopy is the preferred surgical approach.
    • In cases of severe damage or suspected malignancy, removal of the ovary and fallopian tube (salpingo-oophorectomy) may be necessary.

6. Ovarian Remnant Syndrome (ORS)

Ovarian remnant syndrome (ORS) occurs when ovarian tissue remains in the pelvic area following surgery on the ovaries, such as oophorectomy or salpingo-oophorectomy.

  • Causes:

    • Factors contributing to the presence of ovarian remnants include adhesions, bleeding during surgery, anatomic variations, or surgical technique.
  • Symptoms:

    • Pelvic pain is the most common symptom.
    • Sensation of a pelvic mass.
    • Absence of expected menopausal symptoms after surgery.
    • Symptoms resembling endometriosis, including pain during sex, urination, or bowel movements, and digestive symptoms.
  • Diagnosis:

    • History of previous ovarian surgery.
    • Pelvic ultrasound to detect pelvic mass.
    • Laparoscopy for definitive diagnosis and tissue sample collection.
  • Treatment:

    • Surgical removal of remaining ovarian tissue- Hormone therapy to suppress ovulation and alleviate symptoms if surgery is not recommended or desired.

7. Referred Pain

Referred pain occurs when pain originating from one area of the body is felt in another location. The ovaries, located near various organs and body parts, can experience referred pain from different medical conditions.

  • Causes:

    • Referred pain is still not fully understood but is thought to occur due to overlapping or converging nerve pathways in the body.
  • Examples of conditions causing referred pain in the ovarian area:

    • Appendicitis: Pain near the belly button or on the right side, along with loss of appetite, constipation, and signs of infection.
    • Constipation: Infrequent bowel movements, hard stools, straining, and feeling of incomplete bowel emptying.
    • Kidney stones: Severe pain focused on the side and back near the ribs, along with additional symptoms like blood in urine, waves of pain, and fever or chills.
    • Pregnancy: Missed period, breast tenderness, nausea, fatigue, and possible ectopic pregnancy with severe pain and shoulder discomfort.
    • Urinary tract infection (UTI): Pelvic pain, frequent urination, burning sensation while urinating, and cloudy urine.
  • Diagnosis:

    • Medical history, physical examination, and pelvic exam.
    • Tests such as blood, urine, pregnancy tests, and imaging (ultrasound, CT scan, or MRI) to evaluate pelvic and abdominal tissues.
  • Treatment:

    • Treatment depends on the underlying condition causing the referred pain.
    • Addressing the specific condition through appropriate medical interventions and management.

Conclusion:

Understanding the potential causes of ovary pain is crucial for timely diagnosis and treatment. Conditions such as pelvic inflammatory disease, ovarian torsion, ovarian remnant syndrome, and referred pain can contribute to ovary-related discomfort. Seeking medical attention and appropriate diagnostic tests can help identify the underlying cause and guide effective treatment strategies. In the next sections, we will explore additional factors that can cause ovary pain and discuss their symptoms, diagnosis, and treatment options.

Is it Ovarian Cancer?

While ovary pain can be a cause for concern, it’s important to note that ovarian cancer is relatively rare. The lifetime risk for ovarian cancer is about 1 in 78 for women, with the majority of cases occurring in women aged 63 or older. The rate of ovarian cancer diagnosis has been declining over the years.

Risk Factors for Ovarian Cancer:

Several factors may increase the risk of developing ovarian cancer, including:

  • Family history of ovarian cancer
  • Presence of certain genetic changes
  • Overweight or obesity
  • Endometriosis
  • Nulliparity (never having children) or late childbirth
  • Hormone replacement therapy after menopause or fertility treatments
  • Smoking cigarettes

If you have a family history of ovarian cancer, it is advisable to consult with your doctor or a genetic counselor to assess your individual risk.

Symptoms:

In the early stages, ovarian cancer may not present noticeable symptoms. However, as the cancer progresses, common symptoms may include:

  • Abdominal bloating or swelling
  • Pelvic or abdominal pain
  • Feeling full quickly while eating
  • Frequent urination

Additional symptoms that may occur with ovarian cancer include fatigue, pain during sex, back pain, changes in menstrual periods, unintentional weight loss, and digestive disturbances. These symptoms may persist and differ from your usual experiences.

If you have persistent and concerning symptoms, it is crucial to schedule an appointment with your doctor to discuss them. Early detection plays a vital role in successful cancer treatment.

Diagnosis:

To diagnose ovarian cancer, your doctor will begin with a comprehensive medical history and physical examination, including a pelvic exam to detect any abnormalities or masses. Imaging tests such as ultrasound, MRI, CT scan, or PET scan can help visualize the ovaries and surrounding organs.

A blood test measuring the CA125 marker, often elevated in ovarian cancer, may be ordered. A biopsy of ovarian tissue is necessary for definitive diagnosis and staging. The tissue sample will be examined under a microscope for cancerous cells.

Treatment:

Treatment for ovarian cancer typically involves surgery, which may include the removal of the affected ovary and potentially other nearby tissues, such as lymph nodes, fallopian tubes, uterus, cervix, and omentum. Chemotherapy is commonly used to kill or inhibit the growth of cancer cells and may be administered before or after surgery. Targeted therapy, utilizing drugs that target specific proteins on cancer cells, can also be employed in certain cases.

The choice of treatment depends on various factors, such as the type and stage of cancer and the individual’s age and overall health. Collaborate with your doctor to develop an appropriate care plan tailored to your specific situation.

Takeaway:

While ovary pain can arise from various causes, including serious conditions like ovarian cancer, it is essential not to jump to conclusions. Monitoring and understanding your symptoms are crucial. Mild pain can be tracked in a diary, while severe or persistent pain warrants prompt medical attention. Conditions like endometriosis and PID require timely treatment to prevent complications such as infertility.

If you experience sudden and severe pain, fever, or vomiting, seek immediate medical care, as it may indicate a ruptured ovarian cyst or ovarian torsion.

For persistent or recurring pelvic pain that causes concern, consult with your doctor for a comprehensive evaluation, including a pelvic exam and further tests to determine the underlying cause and develop an effective treatment plan. Early detection and appropriate medical intervention can significantly impact the prognosis and successful management of ovarian conditions.

Resources for Further Reading

Websites and Online Resources:

  • Mayo Clinic: A trusted source providing comprehensive information on ovary pain, its causes, diagnosis, and treatment options. Visit Mayo Clinic
  • American College of Obstetricians and Gynecologists (ACOG): Offers reliable information on various gynecological conditions, including ovarian pain and related disorders. Visit ACOG

Books:

  • "The Doctor's Guide to Gynecologic Cancer: Knowledge Is Power" by Nadeem R. Abu-Rustum: Provides valuable insights into gynecologic cancers, including ovarian cancer, with a focus on empowering patients through knowledge. Find the Book
  • "Ovarian Cancer: Your Guide to Taking Control" by Kristine Conner and Lauren Langford: A comprehensive guide for understanding and managing ovarian cancer, offering practical advice and empowering strategies. Find the Book

Academic Journals and Research Papers:

  • "Risk of Ovarian Cancer in Women with Symptoms in Primary Care: Population-Based Case-Control Study" by Willie Hamilton et al. (British Medical Journal, 2009): A research study exploring the risk of ovarian cancer in women presenting with symptoms in primary care. Read the Paper
  • "Management of Ovarian Cysts: A Comparative Review of Guidelines" by Raffaella Petrillo et al. (Ecancermedicalscience, 2019): A comprehensive review comparing guidelines for the management of ovarian cysts, aiding in understanding the different approaches. Read the Paper

Reports and Studies:

  • "The Burden of Gynecologic Diseases in the United States: A Summary Report of National Estimates" by Jennifer H. Burges et al. (American Journal of Obstetrics & Gynecology, 2019): A report providing an overview of the prevalence and impact of gynecologic diseases, including ovarian conditions, in the United States. Read the Report
  • "Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries" by Freddie Bray et al. (CA: A Cancer Journal for Clinicians, 2021): A comprehensive report presenting global statistics on cancer incidence and mortality, including ovarian cancer. Read the Report

Professional Organizations and Associations:

  • American Cancer Society (ACS): A reputable organization offering extensive resources on cancer, including ovarian cancer awareness, prevention, and support services. Visit ACS
  • Society of Gynecologic Oncology (SGO): A professional organization dedicated to the prevention, treatment, and research of gynecologic cancers, providing valuable information on ovarian cancer and advancements in the field. Visit SGO

Available Treatments